EVALUATATION OF THE LEVEL OF VITAMIN C, VITAMIN E AND MALONDIALDEHYDE IN MALE SMOKERS AND NON SMOKERS.
BACKGROUND OF THE STUDY
Burning tobacco and inhaling the smoke is the act of smoking tobacco (consisting of gaseous phases and particles). A broader definition might include inhaling tobacco smoke into one’s mouth before exhaling it, as some people do when using cigars and tobacco pipes. The custom might have started as early as 5000–3000 BC (Nagarajet al., 2014). The most object-specific, self-administered form of addiction and dependence production known to man is probably cigarette smoking. Current estimates indicate that tobacco use results in more than 5 million deaths annually (World Health Organization, 2008).
It is well known that smoking has negative effects on one’s health.
According to studies by Schumacher et al. and others, cigarette smoke contains about 4000 chemicals, including free radicals, poisonous gases, and toxic metals.
2009). Free radicals are thought to be the most dangerous of these constituents because they have an unpaired electron.
are highly reactive and can harm biomolecules and biomembranes through oxidation (Senet al., 2010).
Smoking significantly alters the balance of antioxidants. Antioxidants present in healthy amounts in blood typically limit the amount of oxidative damage. Activated neutrophils released as a result of smoking add to the pool of reactive oxygen species in tobacco smoke, which depletes these antioxidant defenses and causes tissue damage (Kumaret al., 2010).
Organic substance malondialdehyde has the chemical formula CH2 (CHO). This reactive species is a sign of oxidative stress and occurs naturally.