Evaluation Of Current Techniques In Diagnoses Of Human Immune Deficiency Virus Hiv

Evaluation Of Current Techniques In Diagnoses Of Human Immune Deficiency Virus Hiv

Abstract

A study was carried to ascertain the energy of some ways used in opinion of mortal Immunodeficiency contagion( HIV). Two hundred and five samples( 203) were collected from the cases from the university of Nigerian tutoring sanitarium and was analysed using Elisa tackle, which has the capability to descry antibodies and antigens in the cases serum, the Western spots were used as the confirmational test, to the Elisa test, In case where there’s false positive of Elisa test, it’s specific and sensitive, Radioimmunoasay looks for the antigens which are radioactively marker. The cases affect shows that 154 cases out of the 205 diagnosed were negative and only 51 cases were positive. The Elisa tackle were stylish used because of its perceptivity and particularity. It’s veritably cheap and can be fluently seen in the request, unlike the Radiommunoassay which are rare and veritably precious to be used.

Supplements

Chapter One

Preface

The mortal Immunodeficiency contagion( HIV) is the contagion that causes acquired Immunodeficiency pattern( AIDS) a condition that sluggishly destroys the body Immune system and makes the body vulnerable to infections. The contagion is generally called Human Immunodeficiency contagion( HIV) because it destroys the Immune system of the existent which is responsible for guarding the existent from complaint. The immunodeficiency associated with, HIV infection can be enormous, and it’s the major cause of death, due to the disfucntion of vulnerable system. The problem with AIDS is, sits neurological madness complex. HIV is a lentivirus, a group of retrovirus. The family of contagion is known for lafency, patient viremia, infection of the nervous system and weak hot vulnerable system. mortal Immunodeficiency contagion( HIV) is smallultra-microscopic organism that infect living effects and uses them to make clones of itself when one’s Immune system is damaged by HIV, AIDS take place( Gallants, 1999).

HIV was first honored in 1981 in Homosexual men in New York megacity. In the united countries the HIV is now known to have began from chimpanzees, transmission from chimps to mortal. originally, there was wild enterprise about what might be the cause of AIDs, but in 1982, the centre for complaint control had satisfying epidermological substantiation that AIDS was caused by a new contagious agents.

Dulbecco et- al( 1983, located small amounts of the new contagion named Lymphademopalty contagion( LAN) but enough to be used an antigenina blood test which showed that AIDS cases were infected with the contagion. WHO,( 19097), responded that the number of cases living with AIDS has escaculated, a figure of 9000 was verified by may 1997. In African AIDs was first responded in 1982. In Nigerian it was first responded in 1986, among marketable coitus workers in Lagos and calabar. In 2003 the seroprevalence has been on the increase, despite the comprehensive and successful forestallment trouble in numerous part of the would, 4. 1 million new HIV infection was anticipated to have occurs In 2003 alone, which could have been contributed by an estimated 9,020 to 10,000 infection per day.

presently, the health problem in Nigerian considering reports from colorful hospitals particularly, the tertiary hospitals, place AIDS infections in Nigerian at a veritably serious state. the implicit and propensity for wide is enormous and the enervating and negative effect n the frugality, the population order affected the working class and the dependents which constitute the penultimate individualities to the working class. HIV infections in this direction and exposure should be healed as a public exigency in Nigeria.

Meanwhile,Dr. Robert Gallo’s laboratory begin recovering a contagion from AIDS case, and reported the finding in the wisdom journal. A number of these vinal insulated was introduced together into nonstop cell societies to see if a strain of the contagion could replicate in the cells one did replicates and Gallo’s named the contagion HILV. III because of the resemblance to two mortal T- lymphotropic contagions.( Neser, 2001).

By 2004, it was shown that numerous esymtomatic people was infected with contagion and could transmits it and that the epidemic was far more expansive than preliminarily suspected. Blood test was generally available for routine testing to contribute blood. therefore markedly perfecting the safety of blood transfusion and products prepared from pooled blood( peiperls, 1995)

Hypothesis

H.O There’s significant difference in the result of Westernblots( WB), Enzymes Linked Immuno( Elisa) and Radiommuneoassay tackle among HIV carriers.

HI There’s no significant difference in the result of Enzymes linked – immurosorbentassay( Elise), Western spots( WB), and Radommunoasay tackle( RIA) among HIV carriers.

Points And Objects

To evalulate the current ways used in the opinion of mortal Immunodeficiency Contagion( HIV).

To help recommend the stylish and most dependable one seeking HIV

Statement of problems

The major problem with HIV/ AIDs in developing would has been the failure to set realistic precedences with respect to both exploration and control.

As clinical opinion fail to effectively by emphasis on the contagion attack is they’re adding case on HIV infection. Some specific ways are use for the opinion of the HIV infection.

Limitation of the study

this work is carried out in university of Nigeria Teaching sanitarium Enugu( UNTH). There’s lack of finance in the completion of the design work, lack of the design work, lack of the vacuity of time also reduce the period of time used.